About Our Lab Group
We are a research lab at St. John’s University, engaged in field of Non-invasive drug delivery, Nanotechnology, Oral delivery, 3D printing, Targeted Drug Delivery, Pulmonary hypertension, Lung Cancer, Drug discovery and Repurposing. We have a group of researchers including graduate and undergraduate students working together in designing and developing non-invasive local delivery of therapeutics into the lungs. Few of the projects currently going on in the lab include repurposing and efficacy enhancement of FDA-approved drug molecules for lung cancer treatment, targeting nanoparticles for Non-Small Cell Lung Cancer, developing inhalable carriers for pulmonary hypertension, continuous production of lipid-based inhalable carriers for localized antibiotic delivery in cystic fibrosis associated pulmonary infections. The overall goal of these projects is to achieve a localized accumulation of the therapy at the disease site, which is simple enough to be scaled up effortlessly for further studies. Apart from Lung delivery, we are also involved in developing oral drug delivery system using FDA approved polymers, lipids and excipients to enhance solubility, dissolution and permeability for better drug absorption. The ongoing projects include improving bioactivity of the molecule for effective intestinal Permeability and preparing amorphous solid dispersions using melt extrusion and 3D printing technology. We have a diverse research lab, where we are also collaborating with other research groups and investigators from different research expertise including medicinal chemistry, pharmacology, toxicology etc.; and have developed an interdisciplinary research team at St. John’s University.
