CAPABILITIES |
Lab Equipment:
Drug and Formulation Development
|
Analysis
- Ultra-performance liquid chromatography (UPLC) (Waters Acquity)
- UV spectrophotometer (VWR)
- Fluorescent Microscope (EVOS-FL) (In collaboration with Dr Aaron Muth)
- Inverted Microscope (Laxco)
- TECAN multimode microplate reader (in collaboration with Dr. Aaron Muth)
- Next Generation Impactor (NGI) (Copley; MSP Scientific)
- Malvern zetasizer
- DSC/ Differential Scanning Calorimeter (in collaboration with Dr. Senshang Lin)
- PXRD/ Powder X-Ray Diffractometer (in collaboration with Dr. Abu Serajuddin)
- NMR/ Nuclear magnetic resonance
- FTIR/ Fourier-transform infrared spectroscopy
- pH meter
- Semi-micro balance
- Stability chamber (in collaboration with Dr. Abu Serajuddin)
- Western blot facilities (In collaboration with Dr. Aaron Muth)
- Electron Microscopy (SEM, TEM, Cryo-TEM) (In house; and user agreement with CUNY ASRC)
- Atomic Force Microscopy (AFM) (User agreement with CUNY ASRC)
- Micro-CT Scanner (SkyScan 1275) (User agreement with NJIT)
- Molecular Modeling for drug screening (Schrodinger molecular modeling station)
In-vitro Cell Culture
- Biological safety cabinet
- Incubator (Eppendorf)
- Incubator with Oxygen control capability (Eppendorf)
In-vivo
- AAALAC accredited animal facility (Animal Care Center)
- Institutional Animal Care and Use Committee (IACUC)
- Rapid oxygen control (Hypoxia) chambers for animal models (BioSpherix)
- PowerLab Hemodynamic measurement system (ADInstruments)
Lab Techniques:
Drug Development
In-vitro Cell Culture
In-vivo Studies
- Complexation
- Conjugated system
- Polymeric Nanoparticles
- Lipid based formulations
- Micro/Nano-emulsions
- Nanocrystal system
- Liposomes
- Solid Lipid Nanoparticles
- Solid dispersions
In-vitro Cell Culture
- Cytotoxicity
- Cellular uptake
- Clonogenic assay
- Migration assay
- 3D spheroid culture
- Western Blot
- Flow cytometry
- Permeability studies
- Angiogenesis Assay
- Autophagy
- Phospholipid Assay
- Anti-proliferation Assay
- Human Tissue permeability
In-vivo Studies
- Pharmacokinetic studies by multiple administration routes
- Dosage administration by non-invasive intratracheal and pulmonary route
- Tumor models
- Hemodynamic studies for pulmonary hypertension
- Bleomycin induced animal model for pulmonary fibrosis