GUPTA LAB @ SJU
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  • Home
  • Research
  • People
  • Publications & Patents
  • Capabilities
  • Gallery
  • NEWS
  • AAPS Chapter @SJU
  • Jarowski Symposium
  • CONTACT

CAPABILITIES

Lab Equipment:

Drug and Formulation Development
  • Probe sonicator (QSonica)
  • Rotary Evaporator 
  • Probe homogenizer
  • High pressure homogenizer (Nano DeBee)
  • 11 twin-screw extruder (In collaboration with Dr. Abu Serajuddin) (Thermo Scientific)
  • 3D Printer (MakerBot)
  • Refrigerated micro-centrifuges (Eppendorf)
  • Centrifuge
  • ​Incubating shaker (VWR)
Picture
 Analysis
  • Ultra-performance liquid chromatography (UPLC) (Waters Acquity)
  • UV spectrophotometer (VWR)
  • Fluorescent Microscope (EVOS-FL) (In collaboration with Dr Aaron Muth)
  • Inverted Microscope (Laxco)
  • TECAN multimode microplate reader (in collaboration with Dr. Aaron Muth)
  • Next Generation Impactor (NGI) (Copley; MSP Scientific)
  • Malvern zetasizer
  • DSC/ Differential Scanning Calorimeter (in collaboration with Dr. Senshang Lin)
  • PXRD/ Powder X-Ray Diffractometer (in collaboration with Dr. Abu Serajuddin)
  • NMR/ Nuclear magnetic resonance
  • FTIR/ Fourier-transform infrared spectroscopy
  • pH meter
  • Semi-micro balance
  • Stability chamber (in collaboration with Dr. Abu Serajuddin)
  • Western blot facilities (In collaboration with Dr. Aaron Muth)
  • Electron Microscopy (SEM, TEM, Cryo-TEM) (In house; and user agreement with CUNY ASRC)
  • Atomic Force Microscopy (AFM) (User agreement with CUNY ASRC)
  • Micro-CT Scanner (SkyScan 1275) (User agreement with NJIT)
  • Molecular Modeling for drug screening (Schrodinger molecular modeling station)
In-vitro Cell Culture
  • Biological safety cabinet
  • Incubator (Eppendorf)
  • Incubator with Oxygen control capability (Eppendorf)
In-vivo
  • ​AAALAC accredited animal facility (Animal Care Center)
  • Institutional Animal Care and Use Committee (IACUC)
  • Rapid oxygen control (Hypoxia) chambers for animal models (BioSpherix)
  • PowerLab Hemodynamic measurement system (ADInstruments)

Lab Techniques:

Drug Development
  • Complexation
  • Conjugated system
  • Polymeric Nanoparticles
  • Lipid based formulations
  • Micro/Nano-emulsions
  • Nanocrystal system
  • Liposomes
  • Solid Lipid Nanoparticles
  • Solid dispersions

In-vitro Cell Culture
  • Cytotoxicity
  • Cellular uptake
  • Clonogenic assay
  • Migration assay
  • 3D spheroid culture
  • Western Blot
  • Flow cytometry
  • Permeability studies
  • Angiogenesis Assay
  • Autophagy
  • Phospholipid Assay
  • Anti-proliferation Assay
  • Human Tissue permeability

In-vivo Studies
  • Pharmacokinetic studies by multiple administration routes
  • Dosage administration by non-invasive intratracheal and pulmonary route
  • Tumor models
  • Hemodynamic studies for pulmonary hypertension
  • Bleomycin induced animal model for pulmonary fibrosis

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